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The Food and Drug Administration, FDA, has approved the drug Vivitrol for that treatment of opioid dependence according to a news release by them on 10-12-2010.

Using two separate drugs to lose weight can be very effective there are combinations before the FDA now awaiting approval. When dealing with weight-loss and the people who go through it one should err assisting caution and let the FDA do its job and demand some investigation be done so that the public recognizes the side effects and perils associated with the medications before we drive them. Keep in mind that drug companies come in business to make money and that they would say almost anything to keep people on their medications.

Researchers found out that participants taking this drug for the year, lost excess weight within four weeks and have kept the body weight off throughout the 56 weeks in the study. Contrave is often a combination in the drugs naltrexone and bupropion, which usually reflect a whole new trend of weight-loss drugs which are made up of more than one active ingredient, that might make them more effective and safer.

Combo-pilling could be the newest fad or better yet the newest ahead under scrutiny and for that reason it is just more publicly known in recent months, comb-pilling for weight loss has been around since the eighties. The biggest reason that using a combination of pills is starting to become popular could be the fact that as of right now there are not any long term prescription slimming capsules that have been licensed by the FDA other than orlistat. The truly disturbing part is always that doctors are prescribing these combinations of medications and some of the combinations are already rejected or have yet to be approved by the FDA.

Seizures can be a side effect with Contrave and really should not be taken in those with seizure disorders. The drug may also raise hypertension and heartrate, and mustn't be used in those with a history of cardiac arrest or stroke in the previous six months. Blood pressure and pulse should also be measured prior to starting the drug and throughout therapy with the drug.

The FDA also warned that Contrave can raise blood pressure level and heart rate and must not be used in patients with uncontrolled high blood pressure level, along with by you are not heart-related and cerebrovascular (circulatory dysfunction impacting the brain) disease. Patients which has a history of cardiac event or stroke in the previous six months, life-threatening arrhythmias, or congestive heart failure were excluded from the clinical trials. Those taking Contrave really should have their heart-rate and pulse monitored regularly. In addition, since compound includes bupropion, Contrave comes which has a boxed warning to alert health care professionals and patients towards the increased likelihood of suicidal thoughts and behaviors related to antidepressant drugs. The warning also notes that serious neuropsychiatric events have been reported in patients taking bupropion for smoking cessation.


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